您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > BMS-911543
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
BMS-911543
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BMS-911543图片
CAS NO:1271022-90-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
BMS911543, BMS 911543
产品介绍

生物活性

BMS-911543是一种有效的、选择性JAK2小分子抑制剂。

靶点信息

JAK2SET-2TYK2JAK3JAK1
1.1 nM60 nM66 nM75 nM360 nM

化学数据

目录号A11241
作用机制Inhibitor (抑制剂)
M. Wt432.52
FormulaC23H28N8O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1271022-90-2
SynonymsBMS911543, BMS 911543
SMILESCCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6

溶解度

In vitroDMSO36 mg/mL (83.23 mM)
WaterInsoluble
Ethanol22 mg/mL (50.86 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.12 mL115.6 mL231.2 mL
0.5 mM4.62 mL23.12 mL46.24 mL
1 mM2.31 mL11.56 mL23.12 mL
5 mM0.46 mL2.31 mL4.62 mL

*The above data is based on the productmolecular weight 432.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.