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Odanacatib(MK-0822)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Odanacatib(MK-0822)图片
CAS NO:603139-19-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
MK0822
产品介绍

生物活性

Odanacatib (MK-0822)是组织蛋白酶K(一种参与骨吸收的酶)的抑制剂。

靶点信息

Cathepsin K (human)Cathepsin K (rabbit)
0.2 nM1 nM

化学数据

目录号A11265
作用机制Inhibitor (抑制剂)
M. Wt525.6
FormulaC25H27F4N3O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.603139-19-1
SynonymsMK0822
SMILESCC(C)(C[C@@H](C(=O)NC1(CC1)C#N)N[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F

溶解度

In vitro (25°C)DMSO96 mg/mL (182.66 mM)
WaterInsoluble
EthanolInsoluble
In vivo4% DMSO+corn oil4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.03 mL95.13 mL190.26 mL
0.5 mM3.81 mL19.03 mL38.05 mL
1 mM1.9 mL9.51 mL19.03 mL
5 mM0.38 mL1.9 mL3.81 mL

*The above data is based on the productmolecular weight 525.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.