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PR-171(Carfilzomib)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PR-171(Carfilzomib)图片
CAS NO:868540-17-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
PR-171-007
产品介绍

生物活性

PR-171 (Carfilzomib)是四肽环氧酮和选择性蛋白酶体抑制剂。它是环氧霉素的类似物。

靶点信息

Proteasome (ANBL-6 cells)
5 nM

化学数据

目录号A11278
作用机制Inhibitor (抑制剂)
M. Wt719.9
FormulaC40H57N5O7
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.868540-17-4
SynonymsPR-171-007
SMILESCC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4

溶解度

In vitro (25°C)DMSO46 mg/mL (63.89 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+30% PEG 300+2%Tween 80+ddH2O1 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM13.89 mL69.45 mL138.91 mL
0.5 mM2.78 mL13.89 mL27.78 mL
1 mM1.39 mL6.95 mL13.89 mL
5 mM0.28 mL1.39 mL2.78 mL

*The above data is based on the productmolecular weight 719.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.