您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Apremilast(CC 10004)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Apremilast(CC 10004)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Apremilast(CC 10004)图片
CAS NO:608141-41-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
200mg电议
10mM * 1mL in DMSO电议

产品名称
CC10004, CC-10004
产品介绍

生物活性

Apremilast (CC 10004)是一种新型的PDE4抑制剂,可抑制人类风湿性滑膜细胞自发产生肿瘤坏死因子-α,并改善实验性关节炎。

化学数据

目录号A11289
作用机制Inhibitor (抑制剂)
M. Wt460.5
FormulaC22H24N2O7S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.608141-41-9
SynonymsCC10004, CC-10004
SMILESCCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC

溶解度

In vitro (25°C)DMSO85 mg/mL (184.58 mM)
WaterInsoluble
EthanolInsoluble
In vivo0.5% CMC+0.25% Tween 8028 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.72 mL108.58 mL217.16 mL
0.5 mM4.34 mL21.72 mL43.43 mL
1 mM2.17 mL10.86 mL21.72 mL
5 mM0.43 mL2.17 mL4.34 mL

*The above data is based on the productmolecular weight 460.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.