生物活性
Alosetron是一种5-HT3拮抗剂，对胃肠道肠道神经系统的5-HT3受体具有拮抗作用。
化学数据
| 目录号 | A11310 |
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 294.4 |
| Formula | C17H18N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 122852-42-0 |
| Synonyms | GR 68755, GR 68755X, Lotronex |
| SMILES | CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=CC=CC=C4N3C |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 33.97 mL | 169.84 mL | 339.67 mL |
| 0.5 mM | 6.79 mL | 33.97 mL | 67.93 mL |
| 1 mM | 3.4 mL | 16.98 mL | 33.97 mL |
| 5 mM | 0.68 mL | 3.4 mL | 6.79 mL |
*The above data is based on the productmolecular weight 294.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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