生物活性
Ciluprevir (BILN 2061)是HCV NS3蛋白酶的一种特定而有效的拟肽抑制剂。
化学数据
| 目录号 | A11343 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 774.9 |
| Formula | C40H50N6O8S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 300832-84-2 |
| Synonyms | BILN-2061, BILN2061 |
| SMILES | CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3)OC)C(=C2)O[C@@H]4C[C@H]5C(=O)N[C@@]6(C[C@H]6/C=C\CCCCC[C@@H](C(=O)N5C4)NC(=O)OC7CCCC7)C(=O)O |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 12.9 mL | 64.52 mL | 129.05 mL |
| 0.5 mM | 2.58 mL | 12.9 mL | 25.81 mL |
| 1 mM | 1.29 mL | 6.45 mL | 12.9 mL |
| 5 mM | 0.26 mL | 1.29 mL | 2.58 mL |
*The above data is based on the productmolecular weight 774.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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