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VE-821
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VE-821图片
CAS NO:1232410-49-9
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
VE821
产品介绍

生物活性

VE-821是一种有效且选择性的蛋白激酶ATR抑制剂。

靶点信息

ATR (Cell-free assay)
13 nM(Ki)

化学数据

目录号A11605
作用机制Inhibitor (抑制剂)
M. Wt468.4
FormulaC18H16N4O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1232410-49-9
SynonymsVE821
SMILESCS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N

溶解度

In vitro (25°C)DMSO65 mg/mL (176.43 mM)
WaterInsoluble
EthanolInsoluble
In vivo30% PEG400+0.5% Tween80+5% propylene glycol28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.35 mL106.75 mL213.49 mL
0.5 mM4.27 mL21.35 mL42.7 mL
1 mM2.13 mL10.67 mL21.35 mL
5 mM0.43 mL2.13 mL4.27 mL

*The above data is based on the productmolecular weight 468.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.