生物活性
Arbidol HCl是抗流感病毒治疗药物。Arbidol抑制膜融合。Arbidol HCl可防止病毒与目标宿主细胞之间的接触。病毒衣壳和靶细胞的细胞膜之间的融合被抑制。这可以防止病毒进入靶细胞,从而保护其免受感染。
化学数据
目录号 | A11663 |
M. Wt | 513.88 |
Formula | C22H25BrN2O3S.HCl |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 131707-23-8 |
SMILES | CCOC(=O)C1=C(N(C2=CC(=C(C(=C21)CN(C)C)O)Br)C)CSC3=CC=CC=C3.Cl |
溶解度
In vitro | DMSO | 97 mg/mL (188.75 mM) |
Water | Insoluble |
Ethanol | 21 mg/mL (40.86 mM) |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 19.46 mL | 97.3 mL | 194.6 mL |
0.5 mM | 3.89 mL | 19.46 mL | 38.92 mL |
1 mM | 1.95 mL | 9.73 mL | 19.46 mL |
5 mM | 0.39 mL | 1.95 mL | 3.89 mL |
*The above data is based on the productmolecular weight 513.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.