CAS NO: | 14357-08-5 |
规格: | 98% |
分子量: | 295.29 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Background:
N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1]. Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)[1]
N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].
[1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6.