CZC-8004是一种广泛的激酶抑制剂,可与多种酪氨酸激酶结合,包括ABL激酶。
CAS:916603-07-1
分子式:C17H16FN5
分子量:309.34
纯度:98%
存储:Store at -20°C
Background:
CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.
[1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC50 values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44.