Kazusamycin A is an antibiotic from Streptomyces and a hydroxy analog of Leptomycin B that demonstrates cytotoxic activity against various human and mouse tumor lines.
CAS:92090-94-3
分子式:C33H48O7
分子量:556.7
纯度:98%
存储:Store at -20°C
Background:
Kazusamycin A is an antibiotic from Streptomyces and a hydroxy analog of Leptomycin B that demonstrates cytotoxic activity against various human and mouse tumor lines. Additionally, at nanomolar concentrations, it inhibits nuclear export and translocation of Rev, a regulatory gene product in the HIV genome.