生物活性
Tegaserod maleate作为运动刺激剂发挥作用，通过激活胃肠道中肠神经系统的5-ht4受体达到其所需的治疗效果。它还能刺激胃肠动力和蠕动反射，据称还能减轻腹痛。此外，替加色罗是5-ht2b受体拮抗剂。
化学数据
| 目录号 | A11743 |
| M. Wt | 417.46 |
| Formula | C16H23N5O.C4H4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 189188-57-6 |
| Synonyms | Zelnorm |
| SMILES | CCCCCN=C(N)NN/C=C/1\C=NC2=C1C=C(C=C2)OC.C(=C\C(=O)O)\C(=O)O |
溶解度
| In vitro | DMSO | 72 mg/mL (172.47 mM) |
| Water | Insoluble |
| Ethanol | 7 mg/mL (16.77 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 23.95 mL | 119.77 mL | 239.54 mL |
| 0.5 mM | 4.79 mL | 23.95 mL | 47.91 mL |
| 1 mM | 2.4 mL | 11.98 mL | 23.95 mL |
| 5 mM | 0.48 mL | 2.4 mL | 4.79 mL |
*The above data is based on the productmolecular weight 417.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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