您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > AZD5363
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
AZD5363
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AZD5363图片
CAS NO:1143532-39-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
AZD 5363, AZD-5363
产品介绍

生物活性

AZD5363是有效的AKT抑制剂,在体内具有药效学活性,有潜力作为单一疗法或联合用药来治疗一系列实体瘤和血液肿瘤。

化学数据

目录号A11759
作用机制Inhibitor (抑制剂)
M. Wt428.9
FormulaC21H25ClN6O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1143532-39-1
SynonymsAZD 5363, AZD-5363
SMILESC1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4

溶解度

In vitroDMSO79 mg/mL (184.18 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.32 mL116.58 mL233.15 mL
0.5 mM4.66 mL23.32 mL46.63 mL
1 mM2.33 mL11.66 mL23.32 mL
5 mM0.47 mL2.33 mL4.66 mL

*The above data is based on the productmolecular weight 428.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.