生物活性
Brinzolamide是一种碳酸酐酶抑制剂,IC50为3.19 nM。
靶点信息
化学数据
目录号 | A11765 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 383.5 |
Formula | C12H21N3O5S3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 138890-62-7 |
Synonyms | Azopt |
SMILES | CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC |
溶解度
In vitro | DMSO | 75 mg/mL (195.56 mM) |
Water | Insoluble |
Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 26.08 mL | 130.38 mL | 260.76 mL |
0.5 mM | 5.22 mL | 26.08 mL | 52.15 mL |
1 mM | 2.61 mL | 13.04 mL | 26.08 mL |
5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
*The above data is based on the productmolecular weight 383.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.