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Prucalopride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Prucalopride图片
CAS NO:179474-81-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
Resolor
产品介绍

生物活性

Prucalopride是一种选择性的,高亲和力的5-HT4受体激动剂,作用于5-HT4A和5-HT4B受体,Ki分别为2.5 nM和8 nM,比作用于5-HT受体亚型选择性高290倍以上。

Targets

TargetValue
5-HT4Aki: 2.5nM
5-HT4Bki: 8nM
5-HT3ki: 3.822μM
5-HT1Aki: >10μM
5-HT1Bki: >10μM
5-HT1Dki: >10μM
5-HT1Eki: >10μM
5-HT1Fki: >10μM
5-HT2Aki: >10μM
5-HT2Bki: >10μM
5-HT2Cki: >10μM
5-HT5Aki: >10μM
5-HT6ki: >10μM
5-HT7ki: >10μM

化学数据

目录号A11771
作用机制Agonist (激动剂)
M. Wt367.9
FormulaC18H26ClN3O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.179474-81-8
SynonymsResolor
SMILESCOCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl

溶解度

In vitroDMSO52 mg/mL (141.35 mM)
WaterInsoluble
Ethanol33 mg/mL (89.7 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM27.18 mL135.91 mL271.81 mL
0.5 mM5.44 mL27.18 mL54.36 mL
1 mM2.72 mL13.59 mL27.18 mL
5 mM0.54 mL2.72 mL5.44 mL

*The above data is based on the productmolecular weight 367.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.