您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > GSK 1210151A(I-BET151)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
GSK 1210151A(I-BET151)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK 1210151A(I-BET151)图片
CAS NO:1300031-49-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
GSK1210151A
产品介绍

生物活性

GSK 1210151A (I-BET151)是溴结构域和额外末端(BET)家族蛋白BRD2,BRD3和BRD4的新型选择性抑制剂。

靶点信息

BRD3 (Cell-free assay)BRD2 (Cell-free assay)BRD4 (Cell-free assay)
0.25 μM0.5 μM0.79 μM

化学数据

目录号A11783
作用机制Inhibitor (抑制剂)
M. Wt415.4
FormulaC23H21N5O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1300031-49-5
SynonymsGSK1210151A
SMILESCC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)[C@H](C)C5=CC=CC=N5)OC

溶解度

In vitroDMSOInsoluble
WaterInsoluble
Ethanol27 mg/mL (64.99 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM24.07 mL120.37 mL240.73 mL
0.5 mM4.81 mL24.07 mL48.15 mL
1 mM2.41 mL12.04 mL24.07 mL
5 mM0.48 mL2.41 mL4.81 mL

*The above data is based on the productmolecular weight 415.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.