Lys-SMCC-DM1是T-DM1的活性代谢物。T-DM1是一个FDA批准的HER2-targetingADC。
CAS：1281816-04-3
分子式：C53H75ClN6O15S
分子量：1103.71
纯度：98%
存储：Store at -20°C
Background:
Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is an FDA approved HER2-targeting ADC.
[1]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
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