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PF-3758309
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF-3758309图片
CAS NO:898044-15-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
PF-03758309
产品介绍

生物活性

PF-3758309是抑制致癌信号和肿瘤生长的小分子p21活化激酶抑制剂。

Targets

TargetValue
PAK4IC50: 1.3nM
PAK1ki: 13.7nM
PAK6ki: 17.1nM
PAK5ki: 18.1nM
PAK4ki: 18.7nM
PAK3IC50: 99nM
PAK2IC50: 190nM

化学数据

目录号A11930
作用机制Inhibitor (抑制剂)
M. Wt490.2
FormulaC25H30N8OS
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.898044-15-0
SynonymsPF-03758309
SMILESCC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)N[C@H](CN(C)C)C5=CC=CC=C5)SC=C2

溶解度

In vitroDMSO87 mg/mL (177.32 mM)
WaterInsoluble
Ethanol87 mg/mL (177.32 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM20.4 mL102 mL204 mL
0.5 mM4.08 mL20.4 mL40.8 mL
1 mM2.04 mL10.2 mL20.4 mL
5 mM0.41 mL2.04 mL4.08 mL

*The above data is based on the productmolecular weight 490.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.