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GW 9662
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GW 9662图片
CAS NO:22978-25-2
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
GW9662, GW-9662
产品介绍

生物活性

GW 9662是一种选择性PPARγ拮抗剂(PPARγ,PPARα和PPARδ的IC50值分别为3.3、32和2000 nM)。

靶点信息

PPARγ (Cell-free assay)PPARα (Cell-free assay)PPARδ (Cell-free assay)
3.3 nM32 nM2 μM

化学数据

目录号A11984
作用机制Antagonist (拮抗剂)
M. Wt276.68
FormulaC13H9N2O3Cl
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.22978-25-2
SynonymsGW9662, GW-9662
SMILESC1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl

溶解度

In vitro (25°C)DMSO48 mg/mL (173.48 mM)
WaterInsoluble
EthanolInsoluble
In vivo5% DMSO+corn oil8 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM36.14 mL180.71 mL361.43 mL
0.5 mM7.23 mL36.14 mL72.29 mL
1 mM3.61 mL18.07 mL36.14 mL
5 mM0.72 mL3.61 mL7.23 mL

*The above data is based on the productmolecular weight 276.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.