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Ro 31-9790(GI4747)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ro 31-9790(GI4747)图片
CAS NO:145337-55-9
规格:98%
分子量:315.41
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Ro31-9790是一种合成的金属蛋白酶(MMP)抑制剂。
CAS:145337-55-9
分子式:C15H29N3O4
分子量:315.41
纯度:98%
存储:Store at -20°C

Background:

Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor.


Ro 31-9790 inhibits L-selectin shedding from mouse and human lymphocytes, Jurkat T cells, and human monocytes with an IC50 of 0.3-0.4 μM on these cell types. The IC50 values obtained for Ro 31-9790 are 4.82 ± 0.75 μM, 1.16 ± 0.27 μM, 0.70 ± 0.06 μM, 4.47± 1.27 μM and 0.38 ± 0.05 μM for mouse lymphocyte L-selectin shedding, Jurkat L-selectin shedding, human lymphocyte L-selectin shedding, human monocyte L-selectin shedding and human monocyte TNF-α shedding[1].



[1]. Borland G, et al. Tissue inhibitor of metalloproteinases-3 inhibits shedding of L-selectin from leukocytes. J Biol Chem. 1999 Jan 29;274(5):2810-5.