Lonapalene(RS4317)是一种有效的5-脂氧合酶(5-LO)抑制剂。
CAS:91431-42-4
分子式:C16H15ClO6
分子量:338.74
纯度:98%
存储:Store at -20°C
Background:
Lonapalene (RS4317) is a topically effective 5-lipoxygenase (5-LO) inhibitor.
Lonapalene (RS4317) may be useful in the treatment of psoriasis, and that leukotriene B4 is a relevant mediator of the pathology of this disease[1].
[1]. Black AK, et al. Pharmacologic and clinical effects of lonapalene (RS 43179), a 5-lipoxygenase inhibitor, in psoriasis. J Invest Dermatol. 1990 Jul;95(1):50-4.