KML-29 is monoacylglycerol lipase inhibitor and an O-hexafluoroisopropyl carbamate analogue of JZL 184. KML-29 potently and selectively inhibits MAGL (IC50s = 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively). KML29 with gabapentin synergistically produces analgesia in mice.
纯度:≥98%
CAS:1380424-42-9