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Combretastatin A4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Combretastatin A4图片
CAS NO:117048-59-6
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品名称
CRC 87-09, NSC 817373
产品介绍

生物活性

Combretastatin A4是在体内和体外的抗肿瘤,抗血管生成和抗转移药。Combretastatin A4是一种微管靶向剂,可与β-微管蛋白结合,Kd为0.4μM。

化学数据

目录号A12601
M. Wt316.35
FormulaC18H20O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.117048-59-6
SynonymsCRC 87-09, NSC 817373
SMILESCOC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O

溶解度

In vitro (25°C)DMSO58 mg/mL (183.34 mM)
WaterInsoluble
EthanolWarmed: 31 mg/mL (97.99 mM)
In vivo5% DMSO+50% PEG 300+ddH2O28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM31.61 mL158.05 mL316.11 mL
0.5 mM6.32 mL31.61 mL63.22 mL
1 mM3.16 mL15.81 mL31.61 mL
5 mM0.63 mL3.16 mL6.32 mL

*The above data is based on the productmolecular weight 316.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.