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MC-Val-Cit-PAB-tubulysin5a
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MC-Val-Cit-PAB-tubulysin5a图片
CAS NO:2055896-86-9
规格:98%
分子量:1283.6
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
MC-Val-Cit-PAB-tubulysin5a 是基于季铵的生物可逆连接,用于靶向递送,可以改善药代动力学和治疗指数。MC-Val-Cit-PAB-tubulysin5a 用于体外和体内有效且稳定的抗体-药物偶联物 (antibody-drug conjugates) 以治疗各种疾病或病症。
CAS:2055896-86-9
分子式:C66H96N11O13S
分子量:1283.6
纯度:98%
存储:Store at -20°C

Background:

MC-Val-Cit-PAB-tubulysin5a has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-tubulysin5a is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].




[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.