生物活性
Parathyroid Hormone 1-34, Human包含hPTH的34个N端残基。 甲状旁腺1（PTH1）和甲状旁腺2（PTH2）受体的激动剂，其在 HEK293 细胞中的 IC50 值为 2 nM。
化学数据
| 目录号 | A12790 |
| M. Wt | 4117.75 |
| Formula | C181H291N55O51S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 52232-67-4 |
| Synonyms | Teriparatide acetate |
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc5c[nH]cn5)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc6ccccc6)C(=O)O |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 2.43 mL | 12.14 mL | 24.29 mL |
| 0.5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
| 1 mM | 0.24 mL | 1.21 mL | 2.43 mL |
| 5 mM | 0.05 mL | 0.24 mL | 0.49 mL |
*The above data is based on the productmolecular weight 4117.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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