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Compound C108
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Compound C108图片
CAS NO:15533-09-2
规格:98%
分子量:270.3
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.
CAS:15533-09-2
分子式:C15H14N2O3
分子量:270.3
纯度:98%
存储:Store at -20°C

Background:

Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. In a mouse xenograft model of breast cancer, compound C108 (1 µM for 24 hours) reduces the proportion of tumor-initiating cells approximately 10-fold compared with untreated cells. In MDA-MB-453 cells, and in the patient-derived xenograft cell line MAXF 401, it diminishes mammosphere formation.