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4'-Ethynyl-2'-deoxyadenosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4'-Ethynyl-2'-deoxyadenosine图片
CAS NO:306305-07-7
规格:98%
分子量:275.26
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA),是一种核苷逆转录酶 (RT) 抑制剂, 是一种抗病毒药物,对耐药HIV变异型具有较强的抑制作用,在MT-4细胞中,EC50 值为 98 nM。
CAS:306305-07-7
分子式:C12H13N5O3
分子量:275.26
纯度:98%
存储:Store at -20°C

Background:

4’-Ethynyl-2’-deoxyadenosine (4’-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1]. EC50: 98 nM (MT-4 cells)[1].




[1]. Ohrui H, et al. 4’-C-substituted-2’-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Curr Drug Targets Infect Disord. 2001 May;1(1):1-10.