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Piperafizine A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Piperafizine A图片
CAS NO:130603-59-7
规格:98%
分子量:304.3
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Piperafizine A is a natural methylated diketopiperazine first isolated from an actinomycete, Streptoverticillium.
CAS:130603-59-7
分子式:C19H16N2O2
分子量:304.3
纯度:98%
存储:Store at -20°C

Background:

Piperafizine A is a natural methylated diketopiperazine first isolated from an actinomycete, Streptoverticillium. It potentiates the cytotoxicity of vincristine , an anti-cancer alkaloid known to be exported from cells by P-glycoprotein. Piperafizine A directs the intracellular accumulation of vincristine in cancer cells to a similar degree as verapamil , a P-glycoprotein inhibitor. The effects of piperafizine A on vincristine accumulation in cancer cells is dose-dependent over a range of 1 to 20 µg/ml.