4',5-Dihydroxyflavone是大豆LOX-1/α-glucosidase的抑制剂,其对大豆LOX-1的Ki值为102.6μM,对酵母α-glucosidase的IC50值为66μM。
CAS:6665-67-4
分子式:C15H10O4
分子量:254.24
纯度:98%
存储:Store at -20°C
Background:
4’,5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.
[1]. Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. [2]. Proen?a C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228.