CAS NO: | 1404-59-7 |
规格: | 98% |
分子量: | 777 |
包装 | 价格(元) |
500ug | 电议 |
2.5mg | 电议 |
Background:
Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport. Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC50 value of 36 µM.