Extracted?from?Hemsleya amabilis Diels root tuber;Store?the?product?in?sealed,?cool?and?dry?condition
CAS：50298-90-3
分子式：C30H48O7
分子量：520.71
纯度：98%
存储：Store at -20°C

Background:

Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1].

参考文献:
[1]. Wang Y, et al. Cucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes. PLoS One. 2014 Feb 25;9(2):e89751.