BF844 is a stabilizer of CLRN1(N48K) which inhibits HSP60 activity, effectively attenuating progressive hearing loss and prevented deafness. References: Alagramam KN, Gopal SR, Geng R, Chen DH, Nemet I, Lee R, Tian G, Miyagi M, Malagu KF, Lock CJ, Esmieu WR, Owens AP, Lindsay NA, Ouwehand K, Albertus F, Fischer DF, Bürli RW, MacLeod AM, Harte WE, Palczewski K, Imanishi Y. A small molecule mitigates hearing loss in a mouse model of Usher syndrome III. Nat Chem Biol. 2016 Jun;12(6):444-51. doi: 10.1038/nchembio.2069. Epub 2016 Apr 25. PubMed PMID: 27110679; PubMed Central PMCID: PMC4871731.

纯度：≥98%

CAS：1404506-35-9