Selective PAR4 agonist
CAS：352017-71-1
分子式：C34H48N8O7
分子量：680.8
纯度：98%
存储：Store at -20°C
Background:
AY-NH2 is a selective agonist of PAR4 with EC50 value of 11 μM [1].
Protease-activated receptor-4 (PAR4) is a member of PARs and plays an important role in mediating cellular effects of thrombin through acting G-proteins i, 12/13 (Rho and Ras activation) and q (calcium signaling) [2].
AY-NH2 is a potent PAR4 agonist and has a higher (
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