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Loreclezole hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Loreclezole hydrochloride图片
CAS NO:117857-45-1
规格:98%
分子量:311
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
GABAA receptor modulator
CAS:117857-45-1
分子式:C10H6Cl3N3.HCl
分子量:311
纯度:98%
存储:Store at -20°C

Background:

Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors[1][2].


参考文献:
[1]. Wingrove PB, et al. The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4569-73.
[2]. Sanna E, et al. Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit. Neuropharmacology. 1996;35(12):1753-60.