NR2B-selective NMDA receptor antagonist
CAS：700878-19-9
分子式：C20H22FN3O.2HCl
分子量：412.33
纯度：98%
存储：Store at -20°C

Background:

NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.

参考文献:
[1]. McCauley JA, et al. NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles. J Med Chem. 2004 Apr 8;47(8):2089-96.