inhibitor of interleukin-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK)
CAS:1407966-77-1
分子式:C30H33N7O2
分子量:523.63
纯度:98%
存储:Store at -20°C
Background:
PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2?nM[1].
参考文献:
[1]. Mamand S, et al. Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma. Sci Rep. 2018 Sep 21;8(1):14216.