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GPR120 Compound A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GPR120 Compound A图片
CAS NO:1599477-75-4
规格:98%
分子量:405.8
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
orally available, high-affinity agonist of GPR120
CAS:1599477-75-4
分子式:C19H23ClF3NO3
分子量:405.8
纯度:98%
存储:Store at -20°C

Background:

GPR120 Compound A is an orally active and high-affinity agonist of GPR120 [1].


G-protein coupled receptor 120 (GPR120, free fatty acid receptor 4/FFAR4) is a G protein-coupled receptor which has been expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. GPR120 has been involved in mediating the anti-inflammatory and insulin-sensitizing effects of omega 3 fatty acids. Deficiency of GPR120 is responsible for reduced fat metabolism, produce anti-inflammatory effects and to acutely potentiate insulin secretion [2].


GPR120 compound A activated GPR120 with the EC50 value of