Valbenazine is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function.
CAS:1025504-45-3
分子式:C24H38N2O4
分子量:418.57
纯度:98%
存储:Store at -20°C
Background:
Valbenazine is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function.
Valbenazine shows a distinctive improvement in tardive dyskinesia symptoms during the successful Phase II trial[1].
参考文献:
[1]. Müller T, et al. Valbenazine granted breakthrough drug status for treating tardive dyskinesia. Expert Opin Investig Drugs. 2015 Jun;24(6):737-42.