Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means 'play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM.
CAS:16496-99-4
分子式:C20H31N.HCl
分子量:321.9
纯度:98%
存储:Store at -20°C
Background:
Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 of 9.5 uM. Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.