15-lipoxygenase (15-LOX) inhibitor
CAS：4079-26-9
分子式：C15H11NS
分子量：237.32
纯度：98%
存储：Store at -20°C
Background:
PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis[1].
参考文献:
[1]. Sendobry SM, et al. Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenaseinhibitor lacking significant antioxidant properties. Br J Pharmacol. 1997 Apr;120(7):1199-206.
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