BH3I-2' is a cell-permeable BH3 mimetic which induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bak BH3 and Bcl-x by targeting the Bcl-x binding pocket. References: Gerasimenko J, Ferdek P, Fischer L, Gukovskaya AS, Pandol SJ. Inhibitors of Bcl-2 protein family deplete ER Ca2+ stores in pancreatic acinar cells. Pflugers Arch. 2010 Oct;460(5):891-900. doi: 10.1007/s00424-010-0859-4. Epub 2010 Jul 9. PubMed PMID: 20617337; PubMed Central PMCID: PMC2937140.

纯度：≥98%

CAS：315195-18-7