您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 15(R)-17-phenyl trinor Prostaglandin F2αisopropyl ester
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
15(R)-17-phenyl trinor Prostaglandin F2αisopropyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15(R)-17-phenyl trinor Prostaglandin F2αisopropyl ester图片
CAS NO:130273-87-9
规格:98%
分子量:430.6
包装与价格:
包装价格(元)
50mg电议
1mg电议
5mg电议
10mg电议

产品介绍
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15.
CAS:130273-87-9
分子式:C26H38O5
分子量:430.6
纯度:98%
存储:Store at -20°C

Background:

15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 µg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.