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Lipid peroxidation inhibitor 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lipid peroxidation inhibitor 1图片
CAS NO:142873-41-4
规格:98%
分子量:364.52
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Lipidperoxidationinhibitor1是一种脂质过氧化(lipidperoxidation)抑制剂,其IC50值为0.07μM。
CAS:142873-41-4
分子式:C24H32N2O
分子量:364.52
纯度:98%
存储:Store at -20°C

Background:

Lipid peroxidation inhibitor 1 is a lipid peroxidation inhibitor with an IC50 of 0.07 μM.


Among the compounds synthesized, Lipid peroxidation inhibitor 1 (26n) exhibits potent effects in the inhibition of lipid peroxidation, with an IC50 of 0.07 μM[1].


Basic molecules 8a and 27 exhibit significant effects against (methamphetamine) MAP-induced hypermotility. Except in these compounds, a phenyl group adjacent to the methyl group in position 2 at a distance seems to be indispensable (compare compounds 26m, o, p with compounds Lipid peroxidation inhibitor 1 (26n), q, r). Among these compounds, Lipid peroxidation inhibitor 1 which has a phenylpiperidinyl group in position 2 is found to be most effective[1].


[1]. Ohkawa S, et al. 5-aminocoumarans: dual inhibitors of lipid peroxidation and dopamine release with protectiveeffects against central nervous system trauma and ischemia. J Med Chem. 1997 Feb 14;40(4):559-73.