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LCZ696(Valsartan)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LCZ696(Valsartan)图片
CAS NO:936623-90-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
10mM * 1mL in DMSO电议

产品名称
LCZ 696, LCZ-696
产品介绍

生物活性

LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂(ARNi),用于治疗高血压和心力衰竭。

靶点信息

RAAS

化学数据

目录号A14206
作用机制Inhibitor (抑制剂)
M. Wt915.98
FormulaC24H29N5O3.C24H29NO5.5/2H2O.3Na
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.936623-90-4
SynonymsLCZ 696, LCZ-696
SMILESCCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O.CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O.O.O.O.[Na+].[Na+].[Na+]

溶解度

In vitroDMSOWarmed: 26 mg/mL (28.38 mM)
WaterWarmed: 88 mg/mL (96.07 mM)
EthanolWarmed: 8 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM10.92 mL54.59 mL109.17 mL
0.5 mM2.18 mL10.92 mL21.83 mL
1 mM1.09 mL5.46 mL10.92 mL
5 mM0.22 mL1.09 mL2.18 mL

*The above data is based on the productmolecular weight 915.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.