Feprazone is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor that is 10-fold selective for COX-2 over COX-1.
CAS：30748-29-9
分子式：C20H20N2O2
分子量：320.4
纯度：98%
存储：Store at -20°C

Background:

Feprazone is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor that is 10-fold selective for COX-2 over COX-1. It reduces LPS-induced prostaglandin E2 production in bovine arterial endothelial cells (IC50 = 1 μM). Oral administration of feprazone (25-100 mg/kg) reduces vascular permeability, edema, and nociception in a rat model of adjuvant-induced arthritis.