MIV-6R is an inhibitor of the menin-MLL interaction. It acts by demonstrating strong and selective effects in MLL leukemia cells and validating specific mechanism of action. References: He S, Senter TJ, Pollock J, Han C, Upadhyay SK, Purohit T, Gogliotti RD, Lindsley CW, Cierpicki T, Stauffer SR, Grembecka J. High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein-protein interaction. J Med Chem. 2014 Feb 27;57(4):1543-56. doi: 10.1021/jm401868d. Epub 2014 Feb 6. PubMed PMID: 24472025; PubMed Central PMCID: PMC3983337.

纯度：≥98%

CAS：1560968-55-9