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C16 Ceramide(d18:1/16:0)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C16 Ceramide(d18:1/16:0)图片
CAS NO:24696-26-2
规格:98%
分子量:537.9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires coordinate action of serine palmitoyl transferase and ceramide synthase.
CAS:24696-26-2
分子式:C34H67NO3
分子量:537.9
纯度:98%
存储:Store at -20°C

Background:

Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires coordinate action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence. C16 ceramide (d18:1/16:0) is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. Accumulation of C16 ceramide (d18:1/16:0) through PPMP (30 μM) or MAPP (50 μM) treatment or from addition of 100 μM synthetic C16 ceramide (d18:1/16:0) induces apoptosis in neutrophil cultures via caspase-3 activation.