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β-Tocotrienol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
β-Tocotrienol图片
CAS NO:490-23-3
规格:98%
分子量:410.6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
antioxidant
CAS:490-23-3
分子式:C28H42O2
分子量:410.6
纯度:98%
存储:Store at -20°C

Background:

β-Tocotrienol is an antioxidant.


There are four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) forms of vitamin E, which is known for its antioxidant activity. Tocotrienols are present in high concentrations in palm oil and wheat germ.


In vitro: The antioxidant activity of the tocopherols and tocotrienols was found to be mainly due to their ability to donate their phenolic hydrogens to lipid free-radicals. Although it is generally agreed that the relative antioxidant activity of the tocopherols was in the order α>β>γ>δ [1].


In vivo: In a previous study, mice were fed a nonpurified control diet, an atherogenic diet alone or the atherogenic diet supplemented with α- and β-tocopherols. Results showed that compared with mice fed the control diet, plasma cholesterol was fourfold greater in mice fed the atherogenic diet. Mice fed the atherogenic diet had much higher VLDL, intermediate density lipoprotein (IDL) and LDL cholesterol and markedly lower HDL cholesterol than the controls. Moreover, in mice fed the atherogenic diet, the hepatic cholesterol plus cholesterol ester concentration was 4.4-fold greater than in mice fed the control diet. Mice fed the atherogenic diet had large atherosclerotic lesions at the level of the aortic valve. The 0.5 g/100 g alpha-tocopherol and palm carotenoid supplements had no effect [2].


Clinical trial: So far, no clinical study has been conducted.


参考文献:
1.  Kamal-Eldin, A., and Appelqvist, L.. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31, 671-701 (1996).
2.  Black, T.M.,Wang, O.,Maeda, N., et al. Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. Journal of Nutrition 130(10), 2420-2426 (2000).