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Ruscogenin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ruscogenin图片
CAS NO:472-11-7
包装:20mg
规格:98%
市场价:3687元
分子量:430.63

产品介绍
Extracted?from?Ophiopogon japonicus(L.f.)Ker-Gawl. root tuber;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:472-11-7
分子式:C27H42O4
分子量:430.63
纯度:98%
存储:Store at -20°C

Background:

Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities[1][2].


参考文献:
[1]. Cao G, et al. Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway. Int J Mol Sci. 2016 Aug 29;17(9). pii: E1418.
[2]. Huang YL, et al. Possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappaB. J Pharmacol Sci. 2008 Oct;108(2):198-205.