(R)-Zanubrutinib是Zanubrutinib的R型对映异构体。Zanubrutinib是一个有选择性的布鲁顿酪氨酸激酶(BTK)抑制剂。
CAS:1691249-44-1
分子式:C27H29N5O3
分子量:471.55
纯度:98%
存储:Store at -20°C
Background:
(R)-Zanubrutinib is the R enantiomer of Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (BTK) inhibitor.
[1]. Wu J, et al. Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor. J Hematol Oncol. 2016 Mar 9;9:21. [2]. Wu J, et al. Second-generation inhibitors of Bruton tyrosine kinase. J Hematol Oncol. 2016 Sep 2;9(1):80.